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Matrixyl and Matrixyl 3000 remain among the most reliably effective anti-aging ingredients available to us. Scientists have found these powerful peptides to double collagen. This endorsement, as well as the anecdotal evidence from many of those who have used it, makes it one of the key actives to look out for. But not all Matrixyl products are made equal. Beware of wild claims of concentrations of 10% or more of Matrixyl (the clinical trials are conducted at 4%). I have made some great discoveries this past year that justify a new 2014 Truth In Aging Five Best with Matrixyl and Matrixyl 3000.
Prana Precious Fluids Eye Serum
There aren’t too many really good eye creams that feature Matrixyl 3000, and so I was excited to discover the newly launched Prana Precious Fluids Eye Serum ($135 in the shop). It is very, very good at tightening the under eye area and firming the lids. The list of anti-aging actives includes the firming peptide ChronNOline, apple stem cells, mushroom antioxidants, ceramidesand a natural skin tightener from chicory root. In fact, it is a winner for Matrixyl 3000 as well as a Five Best eye serum.
Medik8 Firewall
When I first reviewed the Medik8 Firewall ($145 in the shop), I wrote: “I am just going to cut straight to the car chase. Medik8 Firewall works. It really works. It really, really works.” And it still does – with many testimonials from others in the Truth In Aging community. In addition to Matrixyl 3000, for which it was a 2013 Five Best winner, there are other important actives that pack Medik8’s punch. There are tons of skin-repairing ingredients, such as copper, N-acetyl cysteine (helps synthesize gluthiathione, a natural antioxidant), the free-radical-scavenging Lipochroman-6 and resveratrol.
Sciote Peptide+Defense Firming Youth Serum
Sciote Peptide + Defense Firming Youth Serum ($98 in the shop). Sciote makes natural, well-priced products that don’t pull their anti-aging punches. As the name would imply, Peptide+Defense is big on peptides, with a peptide complex from amino acids as well as Matrixyl 3000. I like that there is a natural hyaluronic acid from the cassia angustifolia (senna) plant. Other useful botanicals include horsetail (good for capillaries) and anti-inflammatory gotu kola.
BRAD Biophotonic Sublime Youth Creator Gel-Cream
Matrixyl 3000 is listed as the third ingredient in the very unique BRAD Biophotonic Sublime Youth Creator Gel-Cream ($245 in the shop). Sublime makes my skin feel tighter, firmer and more hydrated in appearance. There’s a very interesting stem cell derived from daisy that is made by the same company that makes Matrixyl. It supposedly protects the skin’s own stem cells and stimulates sirtuin-1 (an enzyme that contributes to the longevity of cells). Periwinkle is one of many botanicals, and it can reduce inflammation and act as an astringent. (Note that this gel/cream has retinol.)
Osmotics Blue Copper 5 Prime
Osmotics Blue Copper 5 Prime ($135 in the shop) is a new favorite of mine. It has been designed for women over 40 dealing with hormonal aging. As well as Matrixyl 3000, there is a newish peptide acetyl tetrapeptide-2, which compensates for hormone loss and helps the skin stay firm. This heavy hitting serum also has a potent form of copper peptides, an epidermal growth factor and artichoke leaf for increasing the skin’s thickness.
October 14, 2014
by Marta
Hi Karen, as mentioned in the article, Sederma (the manufacturer of Matrixyl and M3000) specifically recommends 4%. The recommendations here are at that level. This is a good opportunity to address the question of cost. Matrixyl and especially Matrixyl 3000 are very expensive raw ingredients and 4% is actually a high amount. Very often an active is used at 1% or less. That's why the selection here are relatively highly priced.
October 14, 2014
by Karen
It would be nice if you listed the concentration of key ingredients like matrixyl 3000 for these products. I hear the company that produces matrixly recommend 3-8% concentration. If I'm going to spend that kind of money on skin cream from your website, that is info I would like to know. Thanks.
June 25, 2014
by Christina
Thanks for your comment, Marty. You might be interested in this recent article by Marta, where she rounds up effective, high-quality products in the TIA shop that are all under $50!
http://www.truthinaging.com/review/beauty-bargains
June 25, 2014
by Marty
Marta - thanks for these helpful lists on what products are best for what issues. I do have a request however, that I know many who love your site share. Would it be possible to you to test and review (and hopefully recommend) products at a lower price point? With so much of your skincare being over $100 and more, it either knocks them all out of range for some or limits many more to just one. I know there is decent skincare out there that is not as highly priced and you would encompass many more followers' ability to buy, if you would try to test and review some of them. With the majority of the prices here being what they are, your site is starting to give the appearance of being geared for a more selective group of customers. Thanks for your consideration.
June 24, 2014
by Sheikha
My pet peeve, please state what age group each cream/serum is ideal for!!